Harmony Test

Harmony is a new DNA-based blood test that measures the risk of Down syndrome (trisomy 21) from as early as 10 weeks in pregnancy.

Harmony is more accurate than traditional Down syndrome blood tests and much less likely to give a false-positive result. That means there will be much less chance your doctor would recommend follow-up testing, such as amniocentesis.

Harmony also tests for two other genetic conditions, trisomy 18 (Edward syndrome) and trisomy 13 (Patau syndrome).

In addition, with Harmony you have the option to evaluate X and Y sex chromosomes.

 

Three steps to clear answers

While other commonly used tests for Down syndrome are performed later in pregnancy and require multiple office visits, Harmony delivers clear answers as early as the first trimester with a single blood draw.

  • A maternal blood sample is taken at week ten of pregnancy, or later.
  • DNA in the sample is analyzed using proprietary Harmony technology.
  • Test results are reported to your provider in 10-12 business days or less.

 

Getting your test results

The Harmony test gives clear answers about the risk to your pregnancy of trisomies 21 (Down syndrome), 18, and 13.

Once the analysis is completed, your provider receives the results and shares them with you.

If you also selected analysis of X and Y sex chromosomes, those results are provided as well.

 

Harmony analyzes DNA

During pregnancy, the mother's blood contains fragments of the developing baby’s DNA. Harmony is a new type of test that analyzes this DNA in a blood sample to predict the risk of Down syndrome (trisomy 21), as well as trisomies 18 and 13, in the pregnancy.

 

A proprietary DNA-based methodology

Harmony Prenatal Test relies on a proprietary targeted DNA-based technology to provide exceptionally accurate results.

  • Cell-free DNA—short DNA fragments—of the mother and the fetus circulate in maternal blood
  • Harmony analyzes fragments from specific chromosomes, rather than all chromosomes
  • Targeted analysis results in higher throughput and accurate trisomy risk assessment